Predictive value of Doppler Renal Resistive Index for Prediction of Acute Kidney Injury in Septic Patients in Intensive Care Unit

Abstract

This was a prospective descriptive study conducted on 150 ICU patients with sepsis; to evaluate prediction value of renal resistive index in detection of acute kidney injury. Measuring flow resistance in the renal circulation, Renal Resistive Index (RRI) could become part of vital organ function assessment using Doppler ultrasound. We found that; the mean age of all patients was (38.4 ± 13.5) years. Regarding gender of the patients, the majority (62.7%) of patients were males; while (37.3%) were females. Regarding basic clinical data; the average MAP was (57.6 ± 14.8) mmHg, the average APACHE score was (14.6 ± 3.7), and the average SOFA score was (4.2 ± 0.92). Regarding comorbidities; (24.7%) of patients had septic shock, (20%) had DM, (34%) had HTN, and (14.7%) had IHD. Comparative study between the 2 groups revealed: • Non-significant difference as regards age and sex of the patients (p > 0.05). • Highly significant decrease in MAP in B group “high RRI”; compared to A group “normal RRI” (p = 0.0079). • Highly significant increase in septic shock, APACHE and SOFA scores in B group “high RRI”; compared to A group “normal RRI” (p < 0.05 respectively). • Highly significant increase in creatinine level in B group “high RRI”; compared to A group “normal RRI” (p < 0.0001). • Non-significant difference as regards all the remaining laboratory variables (p > 0.05). • Highly significant increase in LOS and 28-day mortality rate, in B group “high RRI”; compared to A group “normal RRI” (p < 0.01 respectively). • Highly significant increase in AKI incidence, in B group “high RRI”; compared to A group “normal RRI” (p < 0.0001).