Evaluation of lmmunonephelometric and Immunoturbidimetric Methods for Estimation of Soluble Transferrin Receptor In Serum

Abstract

The soluble transferrin receptors are ofthe most important markers in iron deficiency anaemia. It is related to the intact receptors concentration. This study was undertaken to evaluate immunoturbidimetric, immunonephelometric , ELISA methods for estimation ofsTtR. In precision study, the immunoturbidini.'l:tric method showed an excellent C.V of 4.46% & 3.4% respectively. As for Immunonephelometric method it was 4.3% for the high control, but was unacceptally high for the low control18%. For the ELISA method, it was acceptable (10% & 5%). The LDL was acceptable for both lmunoturbidimetric (0.07 mg/L), and ELISA methods (47.6 u/L).