Aminophylline Versus Acetaminophen In The Treatment Of Post-Dural Puncture Headache

Abstract

¬Neuraxial anaesthesia is very effective anaesthesia especially if the surgical site below the umbilicus level. PDPH is one of the most common complications of diagnostic, therapeutic or inadvertent lumbar punctures. PDPH is defined as any headache after a lumbar puncture that worsens within 15 minutes of sitting or standing and is relieved within 15 minutes of lying down. Ninety per cent of PDPH occur within three days of the procedure and 66% start in the first 48 hours. The features of PDPH are often variable. PDPH may be accompanied by neck stiffness, tinnitus, hearing loss, photophobia or nausea; other features, such as the location and duration, are also unpredictable. Many Pharmacologic interventions offer a safe and effective alternative to an EBP. Pharmacological options for management include NSAIDs, steroids, Methylxanthine derivatives, sumatriptans, gabapentinoids & Neostigmine – Atropine.