The Role of Magnetic Resonance Imaging in Evaluation of Chemotherapy Induced Posterior Reversible Encephalopathy Syndrome in Cancer Patients

Abstract

RES has been increasingly recognized within the cancer population. There are several chemotherapeutic agents have been associated with PRES. Although PRES was originally described in association with HTN. It has been also described with a variety of systemic conditions, including autoimmune diseases, septic shock, and chemotherapy. Nowadays awareness of PRES is increasing as a complication of chemotherapy particularly in pediatric oncology, but it still less frequently recogonized in adult oncology, and suspecting this condition early when there are neurological changes and the above-mentioned risk factors is important to avoid potential, nonreversible complications. PRES has various non specific Symptoms but most commonly presented with seizures as well as altered mental status, headache and visual changes. The aim of our study is to evaluate the role of MR radiological features of PRES in cancer patients and to emphasize the recognition of atypical patterns. Brain MRI is considered the most important diagnostic tool for early diagnosis and follow-up of patients with PRES . The typical pattern is relatively symmetrical cortical/