Lidocaine Prilocaine Cream versus Lidocaine Injection on Reduction of Perineal Pain during Perineal Tears Repair after Childbirth: A Randomized Clinical Trial Study

Abstract

ain of perineal trauma is considered one of the most health problems. Perineal trauma refers to any damage to the genitalia during vaginal delivery either spontaneously or due to episiotomy. Different methods are applied to reduce pain during labor and the pain caused by episiotomy. Some of these methods include non-pharmaceutical methods such as hot packs, cold water compresses, and massage of the perineum, and pharmaceutical methods such as the use of local anesthetics (lidocaine gel or spray, lidocaine injection with or without vasoconstrictor). The most commonly used method is the injection of topical anesthetic. On the other hand, some other medical specialties have reported that the use of topical products such as sprays, gels, and creams/ointments are good alternatives to injectable anesthetics. Topical analgesia means localized delivery of drug to the skin for pain relief through a local action on the peripheral sensory nerves and adjacent tissues. They carry many advantages as inducing a local effect without considerable systemic absorption, safety, ease of use and effectiveness. Lidocaine prilocaine (LP) cream is an oil/water emulsion in which the oil phase consists of eutectic mixture of two different anesthetics: lidocaine 2.5% and prilocaine 2.5% in a