Assessment of Urinary Iodine Level and its relation to thyroid Function in sample of Egyptian Pregnant Females in 1st Trimester

Abstract

Iodine is a micronutrient that has been identified as being essential for optimal fetal neurodevelopment. Iodine requirements increase for women during pregnancy because of the need for a rise in the production of maternal thyroid hormones, the transfer of iodine to the fetus, and increased renal clearance. Maternal iodine deficiency, predominantly in the first trimester of pregnancy, has been linked to long-term and persistent suboptimal development of the child, particularly with reference to cognitive, language and motor development ID is directly linked to dietary intake and at the severe end of the continuum it causes cretinism, a severe form of intellectual impairment. At the milder end of the continuum, GID is associated more with reduced speed of neuro-transmitting and therefore reduced working memory capacity, attention and response inhibition, resulting in what may be termed Gestational Iodine Deficiency Processing Disorder The aim of work of the present study was at assessing the level of urinary iodine in 1st trimester of pregnancy and its relationship with thyroid hormones level and autoimmunity status. To elucidate this aim,100 healthy pregnant female in their 1st trimester of pregnancy were included in the study