Antimicrobial activity of gold and silver nanoparticles produced microbially

Abstract

This work involved the study of the ability of different bacteria isolated from gold and silver-rich dust from jewelry workshops in jewish quarter, El Sagha, Egypt to synthesize gold and silver nanoparticles outside the cell and the factors that affect the biosynthesis of both gold and silver nanoparticles, also, study the effect of these nanoparticles against multidrug resistant pathogenic strains, Comparing antimicrobial efficiency of different antibiotics with AuNPs and AgNPs and the main objective of this study was concentrated on the effect of Combination between non-effective antibiotics and AuNPs or AgNPs against multidrug resistant pathogenic strains. Three out of twenty examined bacterial isolates were selected to produce AuNPs. The MAM-S20 bacterial isolate was the most potent isolate for AuNPs production outside the cell and was identified by 16SrRNA asProvidenicavermicola with 98% similarity with Providenicavermicola strain OP1. with accession No. MN900605.1.