Study of Pentraxin-3 as an Early Marker of Diabetic Vascular Complications in Children and Adolescents with Type 1 Diabetes Mellitus

Abstract

Diabetes is a complex, chronic illness requiring continuous medical care with multifactorial risk-reduction strategies beyond glycemic control. Complications of T1DM: (I) Acute complications 1. Diabetic ketoacidosis (DKA). 2. Hypoglycemia. 3. Hyperosmolar non-ketotic coma. (II) Chronic complications: {A} Macrovascular complications: CVD is a more common cause of death than microvascular complications in populations with diabetes. There is evidence for a cardiovascular benefit of intensive glycemic control after long-term follow-up of cohorts treated early in the course of type 1 diabetes {B} Microvascular complications: A1- Diabetic retinopathy. A2- Diabetic neuropathy. A3- Diabetic nephropathy.