“Evaluation of The Antibacterial Effect, Compressive Strength and Fluoride Release of Added Zinc Oxide Nanoparticles Versus Silver Nanoparticles to Conventional Glass Ionomer”

Abstract

GICs are a group of dental cements suitable for the use in patients with high caries prevalence. Since GIC introduction, GICs had undergone several modifications to enhance their properties and decrease their limitations(65). Nanotechnology involves the use of materials which have the size in the range of 1–100 nm, recent studies have suggested that incorporation of nano-sized particles can improve the mechanical and chemical properties of dental restorative material(65).

The present study purpose is to assess the anti-bacterial effect, compressive strength and fluoride release of conventional glass ionomer with and without addition of nanoparticles in an in-vitro conditions.

The experimental GIC was prepared by mixing 3wt% of silver nanoparticles and 3wt% of zinc oxide nanoparticles within the powder of conventional GIC. This resulted in creation of two groups from the modified materials, in addition to the unmodified conventional glass ionomer as a control group.

In this study Specimens were prepared using Teflon molds constructed for each test. Antibacterial test against S.Mutans was performed using disc diffusion test and assessed by inhibition zone diameter within 24 hours. Compressive strength test was done by using universal testing machine. Fluoride ion release was measured after 24 hours, 7 days and 30 days intervals using the ion chromatography system. Results showed that silver NPs group and ZnO NPs group showed significant anti-bacterial effect, as silver NPs group showed higher antibacterial mean value of inhibition zone.