Clinical and Laboratory Studies on Thyroid Gland Hormones in Dogs in Health and Disease

Abstract

Four hundred forty one dogs of different ages, sex and breeds in different seasons, during the period of 2018 till 2020. These animals were admitted to a private clinic in Cairo Governorate, Egypt. They were subjected to a comprehensive clinical examination to detect different hypothyroidism features. They were divided into 38 dogs apparently healthy and considered as control group while 403 with variable manifestation can be referred to hypothyroidism and classified into 13 features. Blood samples were collected from the jugular or cephalic vein from each dog in lithium heparin cups or on plain tube for serum separation. Heparinized blood or serum were used to determine TT4 levels using veterinary specific kits (Catalyst total T4 slide) and Catalyst One Chemistry Analyzer, IDEXX laboratories , Inc, Westbrook, Maine, according to the manufacturer’s instruction, for screening incidence of hypothyroidism in the examined dogs. Data are represented as Mean ± SE, data set was compared using graphpad PRISM, P value < 0.05 considered significant.