Synthesis and characterization of some novel transition metal complexes and studying their biological efficiency

Abstract

Details of the studies on the synthesis, spectral characterization and analytical applications of some new transition metal complexes of the Schiff bases derived from 2-hydroxy-1-napthaldehyde are presented in this thesis Schiff-bases are important material for inorganic chemists as these are widely used in medicinal inorganic chemistry due to their diverse biological, pharmacological, antitumor activities. Recently, there has been tremendous interest in studies related to the interaction of transition metal ions with nucleic acid because of their relevance in the development of new reagents for biotechnology and medicine. The thesis is divided to three chapters and pronounced as follows: Chapter I: Introduction and Literature Review In chapter I, involves a general introduction to Schiff bases and their transition metal complexes. Brief discussion about the applications of Schiff bases and their metal complexes in various field, importance of Schiff base transition metal complexes, antioxidants and its biological importance are included in this chapter, preparation of Schiff base and its complexes derived from previous studies of some research projects, a literature review on detection and determination Al3+ ions by using