Predictors and Outcomes of Multidrug-Resistant Gram-Negative Bacterial Bloodstream Infections in Pediatric Oncology Patients

Abstract

Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, it is the second leading cause of death globally. Pediatric patients with cancer are at great risk of infection either from disease process or after being immuno-suppressed by chemotherapy and radiotherapy, this is especially with non-pathogenic gram negative and multidrug resistant (MDR) pathogens. This raises the need for careful local antibiotic stewardship and infection control programs The current study was conducted to detect the frequency and risk factors of multidrug resistant gram negative bacteria (MDR-GNB) infections at the Pediatric Oncology Department and to identify the patterns of resistance of different pathogens to commonly used antimicrobials and detect the risk factors and outcomes of MDR-GNB infectio