STUDY Of ATRIAL NA-MIMETIC PEPTIDE LEVEL IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE DURING STABLE AND DECOMPENSATED CONDITIONS

Abstract

Atrial natriuretic peptid (ANP) is a recently discovered polypeptide. Little has been written about this peptid in lung diseases, although expanded researches were done in the different cardiac conditions. It is an important hormonal regulator of salt and water and of arterial blood pressure (Di-Nardo et al, 1992). In the lung, it is synthesized by type II alveolar cells and respiratory epithelial cells. It is also localized in the smooth muscle cells of the pulmonary veins