Analytical studies of some nitrogen containing drugs

Abstract

This work has been canicd cut to determine desloratadine (DIES) as an ariuliistainiiiic di uii in pun; and pliar[ii;ii.e<j|ic;il preparations usin^ new spectio photometric and HPIX procedures. The pectrophotormciric methods arc carried out iv the reactions of"[his drug via charge translcr compilation with 2.4-dichbro-iS- 11 itrcphelie] (DCNP): 2.4- dmilroplicnol (DNP) and picric acid (PA) reagenls find through ion-pair formation with bromocresol green (BCG) and bromolhymol blue (RTB) reagents The sensitivity of these procedures has been improved and the oplinium practical conditions for the analysis of this diug are selected Also optimum conditions for the dercrinination of DE5 dniy. in pure- form a:id phjrmiiceutical piepiuat ions using H IM C is studied