Paracetamol versus Nalbuphine in Relieving Pain in the First Stage of Labour in Primigravida: A Double Blinded Randomized Controlled Trial

Abstract

Labor pain is one of the major issues obstetricians face all over the globe requiring proper management protocols to improve and enhance level of medical care offered for women particularly in active phase of labor. Pain during labor originates from various sources such as uterine contractions and cervical dilatation proper control of pain is beneficial for proper normal progress of labor without jeopardizing maternal or fetal clinical status. Various agents have been extensively tested and investigated with different response levels (Bataille et al., 2014; ACOG, 2016). Opioids are considered one of the cornerstone agents implemented in management of pain during labor having the feasibility to be administered intravenously or intramuscularly. Nalbuphine Hydrochloride injection is one of the opioid family commonly used in laboring cases that controls severe levels of pain however some case scenarios face undesirable side effects such as vomiting and fetal distress that is considered a critical issue in obstetric practice; however, proper protocol implementation in administration of the agent minimizes the harmful possible side effects and reduces the draw backs (Aweda et al., 2016).