Evaluation of galectins gene expression in acute myeloid leukemia patients
Mahmoud Moustafa Abd-elfatah;
Abstract
Acute myeloid leukemia (AML) is a malignant
hematopoietic disease characterized by an overproduction of
immature myeloid cells, (myeloblasts) in the bone marrow in
which precursors of blood cells are blocked in an early stage of
maturation. AML is a disease of older adults with median range
68 years. Galectins family are animal lectins which affect a wide
range of cellular functions. Many galectins are repeatedly
reported in several physiological changes and diseases including
cancer. In AML, there is a big focus on galectins-3 and -9, but not
the other galectins.
Patients and Methods: Bone marrow (BM) and corresponding
hematopoietic disease characterized by an overproduction of
immature myeloid cells, (myeloblasts) in the bone marrow in
which precursors of blood cells are blocked in an early stage of
maturation. AML is a disease of older adults with median range
68 years. Galectins family are animal lectins which affect a wide
range of cellular functions. Many galectins are repeatedly
reported in several physiological changes and diseases including
cancer. In AML, there is a big focus on galectins-3 and -9, but not
the other galectins.
Patients and Methods: Bone marrow (BM) and corresponding
Other data
| Title | Evaluation of galectins gene expression in acute myeloid leukemia patients | Other Titles | تقييم التغيير الجينى للجلاكتنات فى مرضى سرطان الدم الميلودى الحاد | Authors | Mahmoud Moustafa Abd-elfatah | Issue Date | 2020 |
Attached Files
| File | Size | Format | |
|---|---|---|---|
| BB2373.pdf | 860.28 kB | Adobe PDF | View/Open |
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