Rs12039395 Variant Influences the Expression of hsa-miR-181a-5p and PTEN Toward Colorectal Cancer Risk
El-Korany, Wael A; Zahran, Walid E; Alm El-Din, Mohamed A; Al-Shenawy, Hanan A; Soliman, Ahmed F;
Abstract
Single nucleotide polymorphisms (SNPs) in microRNA (miRNA) genes could alter miRNA expression levels or processing and, thus, may contribute to colorectal cancer (CRC) development. Therefore, this study aimed to examine whether the MIR181A1 genomic sequence possesses SNPs that can affect the expression of hsa-miR-181a-5p and, subsequently, impact its targets and associate with CRC risk.
Other data
| Title | Rs12039395 Variant Influences the Expression of hsa-miR-181a-5p and PTEN Toward Colorectal Cancer Risk | Authors | El-Korany, Wael A; Zahran, Walid E; Alm El-Din, Mohamed A; Al-Shenawy, Hanan A; Soliman, Ahmed F | Keywords | Colorectal cancer (CRC);Phosphatase and tensin homolog (PTEN);Single nucleotide polymorphism (SNP);miR-181a | Issue Date | 28-Jun-2024 | Journal | Digestive diseases and sciences | ISSN | 0163-2116 1573-2568 |
DOI | 10.1007/s10620-024-08517-3 | PubMed ID | 38940971 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.