Spotlights on Pharmacogenetics of Schizophrenia and Depressed Mood

Abstract

When polymorphism occur in genes that encoding drug transporters or drug metabolism which are determinants to drug pharmacokinetic it is called pharmacokinetic genetic polymorphism which is more common and much more clinically important. The clinical importance of polymorphism may occur in genes that encoding drug receptors or cell signaling pathways which are determinants to drug pharmacodynamics and so called pharmacodynamic genetic polymorphism. On the other hand, both pharmacokinetic/pharmacodynamics (PK/PD) genetic polymorphism.