The significance of added ADC value to conventional MR imaging in differentiation between benign and malignant ovarian neoplasms

Abstract

Purpose To highlight the role of ADC value measurement in differentiating benign from malignant ovarian tumors. Materials and methods Twenty patients with ovarian neoplasms underwent conventional MRI including ADC value calculation before surgery. Retrospective analysis of the pathological specimen with lesion morphology, signal characteristics, enhancement criteria and correlation with the appearance at DWI followed by ADC value measurement were obtained. Results Twenty patients with ovarian mass lesions were included. They were divided into purely solid, purely cystic and complex solid/cystic lesions. All solid malignant lesions showed diffusion restriction as well as the wall and septations of most malignant cystic lesion however, except one case. All benign lesions did not display diffusion restriction in DWI. The best cut off value of ADC to discriminate between benign and malignant lesions was 0.9 with specificity of 100%, sensitivity of 88.9%, NPV of 75%, PPV of 100% and accuracy of 91.7%. Conclusion Addition of ADC value measurement to conventional MRI increases its specificity from 78.6% to 85.7% which could be useful in differentiating benign from malignant lesions. © 2014 Production and hosting by Elsevier B.V.