Danger ahead: the burden of diseases, injuries, and risk factors in the Eastern Mediterranean Region, 1990-2015

Khalil I ; El Bcheraoui C, Charara R, Moradi-Lakeh M, Afshin A, Kassebaum NJ, Collison M, Chew A, Krohn KJ, Daoud F, Colombara D, Foreman KJ, Godwin WW, Kutz M, Mirarefin M, Rao PC, Reiner R, Troeger C, Wang H, Abraha HN, Abu-Elyazeed R, Abu-Raddad LJ, Ahmad Kiadaliri A, Ahmadi A, Ahmed MB, Alam K, Alizadeh-Navaei R, Al-Raddadi R, Altirkawi KA, Alvis-Guzman N, Anber N, Anwari P, Atey TM, Avokpaho EFGA, Bacha U, Bazargan-Hejazi S, Bedi N, Bensenor IM, Berhane A, Bessong PO, Beyene AS, Bhutta ZA, Buckle GC, Butt ZA, Danawi H, Deribew A, Djalalinia S, Dubey M, Endries AY, Eshrati B, Fereshtehnejad SM, Fischer F, Gebrehiwot TT, Gugnani HC, Hamadeh RR, Hamidi S, Husseini A, James SL, Jonas JB, Khader YS, Khan EA, Khan G, Khubchandani J, Kissoon N, Kopec JA, Koyanagi A, Kuate Defo B, Larson HJ, Latif AA, Lunevicius R, Magdy Abd El Razek H, Magdy Abd El Razek M, Majdzadeh R, Majeed A, Malekzadeh R, Memiah P, Memish ZA, Mendoza W, Mengistu DT, Mohammed S, Murthy S, Ngunjiri JW, Ogbo FA, Pourmalek F, Radfar A, Rafay A, Rahimi-Movaghar V, Rai RK, Ram U, Rawaf DL, Rawaf S, Renzaho AMN, Rezaei S, Roshandel G, Safdarian M, Sahraian MA, Salamati P, Samy AM, Sanabria JR, Sartorius B, Sepanlou SG, Shaikh MA, Shigematsu M, Sobaih BHA, Sreeramareddy CT, Sykes BL, Tehrani-Banihashemi A, Temsah MH, Terkawi AS, Tiruye TY, Topor-Madry R, Ukwaja KN, Vollset SE, Wakayo T, Werdecker A, Wiysonge CS, Workicho A, Yaghoubi M, Yaseri M, Yenesew M, Yonemoto N, Younis MZ, Zaki MES, Zein B, Zodpey S, Jumaan AO, Vos T, Hay SI, Naghavi M, Murray CJL, Mokdad AH. ; Samy, Abdallah 


OBJECTIVES: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children's potential livelihood through growth faltering, cognitive impairment, and other sequelae. METHODS: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)-the sum of years of life lost and years lived with disability-for both sexes and all ages. RESULTS: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018-124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4-19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640-79,486). DALYs per 100,000 ranged from 304 (95% UI 228-400) in Kuwait to 38,900 (95% UI 25,900-54,300) in Somalia. CONCLUSIONS: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.

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Issue Date 3-Aug-2017
Journal International journal of public health 
URI http://research.asu.edu.eg/123456789/738

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