Transmission of Leishmania infantum MON-98 to hamsters by the bite of Phlebotomus langeroni Nitzulescu (Diptera: Psychodidae)

El Sawaf, Bahira ; Doha S. ; Imam M. 


Abstract


The ability of Phlebotomus langeroni to successfully acquire and transmit Leishmania infantum MON-98 to hamsters was demonstrated. Sand flies and Leishmania both originated from an infantile visceral leishmaniasis focus in El Agamy Egypt. P. langeroni females were infected by feeding on lesions of needle-inoculated hamster and on infected blood suspension using a chick-skin membrane apparatus. Infection rate of sand flies fed on membrane was 88% compared to 7.8% for flies fed on leishmanial lesion. The transmission to hamster took place by the bites of infective flies taking a second blood meal, on the 8th to 10th day post-feeding. Furthermore, successful transmission was by the bites of flies that took no blood or that took full blood meal. Whereas flies that took full blood meal were not infective as indicated by dissection. In three hamsters, lesions developed after three months. Leishmania amastigotes were demonstrated from the lesion as well as from the liver and spleen of infected hamsters. © 2011 Elsevier B.V.


Other data

Issue Date 1-Jan-2012
Journal Acta Tropica 
URI http://research.asu.edu.eg/123456789/979
DOI 1
44
http://api.elsevier.com/content/abstract/scopus_id/81255160697
121
1873-6254
10.1016/j.actatropica.2011.08.008


Recommend this item

CORE Recommender
3
Citations

7
Views


Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.