Computer Aided Drug Design and Synthesis of New Isoquinolineand Quinoline Diones Derivatives with Expected Antitumor Activity
Ahmed Bakr Abdelwahab;
Abstract
A new series of nine amino isoquinoline-5,8-dione and eleven amino quinoline-5,8-dione derivatives were synthesized starting from isoquinoline and 8-hydroxyquinoline respectively through multi-step reactions. The title compounds (Ia-IXa, Ib-XIb) were prep
Other data
| Title | Computer Aided Drug Design and Synthesis of New Isoquinolineand Quinoline Diones Derivatives with Expected Antitumor Activity | Other Titles | التصميم الدوائى باستخدام الكمبيوتر لتشييد بعض المشتقات الجديدة من الأيزوكينولين والكينولين ديون ذات نشاط بيولوجى متوقع ضد الأورام السرطانية. | Authors | Ahmed Bakr Abdelwahab | Keywords | Computer Aided Drug Design and Synthesis of New Isoquinolineand Quinoline Diones Derivatives with Expected Antitumor Activity | Issue Date | 2011 | Description | A new series of nine amino isoquinoline-5,8-dione and eleven amino quinoline-5,8-dione derivatives were synthesized starting from isoquinoline and 8-hydroxyquinoline respectively through multi-step reactions. The title compounds (Ia-IXa, Ib-XIb) were prep |
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