Design, Synthesis and Docking Study of Certain Quinazoline Based Heterocyles as promising Antitumor Agents-Targeting Tyrosine Kinase

Samar Mohamed Ahmed Mowafy;

Abstract


Three series of substituted 4,6-quinazolinediamine have been designed, synthesized as anti-cancer targeting agents. In the design of the target compounds we aimed to append enamine ester or urea moiety at the six position of quinazoline ring to be capable


Other data

Title Design, Synthesis and Docking Study of Certain Quinazoline Based Heterocyles as promising Antitumor Agents-Targeting Tyrosine Kinase
Other Titles تصميم وتشييد ودراسة موائمة لبعض مشتقات الكينازولين كمضادات للاورام مستهدفه انزيم التايروزين كاينيز
Authors Samar Mohamed Ahmed Mowafy
Keywords Design, Synthesis and Docking Study of Certain Quinazoline Based Heterocyles as promising Antitumor Agents-Targeting Tyrosine Kinase
Issue Date 2012
Description 
Three series of substituted 4,6-quinazolinediamine have been designed, synthesized as anti-cancer targeting agents. In the design of the target compounds we aimed to append enamine ester or urea moiety at the six position of quinazoline ring to be capable

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