Effect of chronic mild stress, an animal model of depression, on Cytochrome P450 1A2 enzyme activity: An in vivo study using caffeine as a metabolic probe.

Ahmed Mustafa Mohamed Hassan;

Abstract


Cytochrome P450 1A2 (CYP1A2) is involved in the metabolism of many medications as well as in the activation of many pro-carcinogens. Modulations of CYP1A2 enzyme activity and inducibility are associated with adverse drug reactions besides increased risks


Other data

Title Effect of chronic mild stress, an animal model of depression, on Cytochrome P450 1A2 enzyme activity: An in vivo study using caffeine as a metabolic probe.
Other Titles تأثير الكرب المزمن البسيط، كنموذج حيواني للاكتئاب، على نشاط إنزيم الصبغيات الخلوية P450 1A2: دراسة في الجسم الحي باستخدام الكافيين كمسبار أيضي.
Authors Ahmed Mustafa Mohamed Hassan
Keywords Effect of chronic mild stress, an animal model of depression, on Cytochrome P450 1A2 enzyme activity: An in vivo study using caffeine as a metabolic probe.
Issue Date 2010
Description 
Cytochrome P450 1A2 (CYP1A2) is involved in the metabolism of many medications as well as in the activation of many pro-carcinogens. Modulations of CYP1A2 enzyme activity and inducibility are associated with adverse drug reactions besides increased risks

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