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| Issue Date | Title | Author(s) |
| Aug-2019 | 3D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluation | Sobhy, Mahitab K; Mowafy, Samar; Lasheen, Deena S. ; Farag, Nahla A; Khaled A M Abouzid |
| 15-May-2013 | Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activity | Lasheen, Deena S. ; Ismail, Mohamed A H; Ismail, Nasser S M; Eid, Sameh; Vleck, Susan; Glenn, Jeffrey S; Watts, Andrew G; Abouzid, Khaled ; Abou El Ella, Dalal |
| 2019 | Apoptosis in cancer: from pathogenesis to discovery of advanced selective Bcl-2 family inhibitors | Abbas, Samaa; Abdou, Nermin; Lasheen, Deena S. ; Abou El Ella, Dalal |
| Sep-2018 | Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancer | Hesham, Heba M; Lasheen, Deena S. ; Khaled A M Abouzid |
| Aug-2016 | Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical Profiles | Hossam, Monia; Lasheen, Deena S. ; Abouzid, Khaled |
| Nov-2016 | Design and Synthesis of 4-Anilinothieno[2,3-d]pyrimidine-Based Compounds as Dual EGFR/HER-2 Inhibitors | Abd El Hadi, Soha R; Lasheen, Deena S. ; Hassan, Mahmoud A; Khaled A M Abouzid |
| 1-Aug-2015 | Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII | Ibrahim, Diaa A; Lasheen, Deena S. ; Zaky, Maysoun Y; Ibrahim, Amany W; Vullo, Daniela; Ceruso, Mariangela; Supuran, Claudiu T; Abou El Ella, Dalal |
| Dec-2019 | Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibition | Elmeligie, Salwa; Aboul-Magd, Asmaa M; Lasheen, Deena S. ; Ibrahim, Tamer M; Abdelghany, Tamer M; Khojah, Sohair M |
| 2023 | Design, Molecular Modelling and Synthesis of Novel Benzothiazole Derivatives as BCL-2 inhibitors | Ismail, Hoda S.; Khalil, Amira; Taha, Rabah A.; Lasheen, Deena S. ; Abou El Ella, Dalal |
| 1-Jun-2018 | Design, synthesis and 3D QSAR based pharmacophore study of novel imatinib analogs as antitumor-apoptotic agents | Fawzy, Iten M; Youssef, Khairia M; Lasheen, Deena S. ; Ismail, Nasser Sm; Abouzid, Khaled |
| Dec-2022 | Design, synthesis, and biological evaluation of new thieno[2,3-d] pyrimidine derivatives as targeted therapy for PI3K with molecular modelling study | Elmenier, Fatma M; Lasheen, Deena ; Abouzid, Khaled |
| 2018 | Design, synthesis, molecular docking study, and biological evaluation of salicylaldimine derivatives as potential histone deacetylases inhibitors (HDACi) and anticancer agents | Hesham, Heba; Lasheen, Deena S. ; Abouzid, Khaled |
| 15-Apr-2016 | Discovery of Potent VEGFR-2 Inhibitors based on Furopyrimidine and Thienopyrimidne Scaffolds as Cancer Targeting Agents | Aziz, Marwa A; Serya, Rabah A T; Lasheen, Deena S. ; Abdel-Aziz, Amal Kamal ; Mansour, Ahmed M; Ahmed Esmat ; Singab A. ; Khaled A M Abouzid |
| 26-Aug-2020 | Elaborating piperazinyl-furopyrimidine based scaffolds as phosphoinositol-3-kinase enzyme alpha (PI3Kα) inhibitors to combat pancreatic cancer | Mansour, Mai A; Lasheen, Deena S. ; Gaber, Hatem M; Khaled A M Abouzid |
| Dec-2018 | Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling | Adel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid |
| 8-Mar-2022 | Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluation | Mansour, Mai A; Oraby, Mamdouh A; Muhammad, Zeinab A; Lasheen, Deena ; Gaber, Hatem M; Khaled A M Abouzid |
| 2018 | Imidazo[2',1':2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study | Ewida, Menna A; Abou El Ella, Dalal ; Lasheen, Deena S. ; Ewida, Heba A; El-Gazzar, Yomna I; El-Subbagh, Hussein I |
| Dec-2022 | Molecular design, synthesis and biological evaluation of novel 1,2,5-trisubstituted benzimidazole derivatives as cytotoxic agents endowed with ABCB1 inhibitory action to overcome multidrug resistance in cancer cells | Abdelhafiz, Abeer H A; Serya, Rabah A T; Lasheen, Deena S. ; Wang, Nessa; Sobeh, Mansour; Wink, Michael; Abouzid, Khaled |
| 5-Oct-2021 | Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies | Eldeeb, Assem H; Abo-Ashour, Mahmoud F; Angeli, Andrea; Bonardi, Alessandro; Elrazaz, Eman ; Nocentini, Alessio; Gratteri, Paola; Abdel-Aziz, Hatem A; Supuran, Claudiu T; Lasheen, Deena S. |
| 1-Dec-2019 | Phosphatidylinositol 3 kinase (PI3K) inhibitors as new weapon to combat cancer | Elmenier, Fatma M; Lasheen, Deena S. ; Khaled A M Abouzid |
| Sep-2018 | Pyrrolopyrimidine, A Multifaceted Scaffold in Cancer Targeted Therapy | Adel, Mai; Serya, Rabah A T; Lasheen, Deena S. ; Abouzid, Khaled |
| Aug-2020 | Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors | Hadi, Soha R Abd El; Soliman, Dalia H; Elrazaz, Eman ; Khaled A M Abouzid ; Lasheen, Deena S. |
| 15-Jul-2018 | Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitors | Milik, Sandra N; Abdel-Aziz, Amal Kamal; Serya, Rabah ; Minucci, Saverio; Lasheen, Deena S. ; Khaled A M Abouzid |
| 15-Jul-2018 | Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinoma | Roy, Joyeeta; Hanafi, Maha; Wang, Dongyao; Luesakul, Urarika; Chai, Yifeng; Muangsin, Nongnuj; Lasheen, Deena S. ; Neamati, Nouri; Khaled A M Abouzid ; Abou El Ella, Dalal ; Shahin, Mai I. |
| 6-Jul-2017 | Synthesis, ADMET Properties, and Biological Evaluation of Benzothiazole Compounds Targeting Chemokine Receptor 2 (CXCR2) | Mehanna, Wesam E; Lu, Tiangong; Debnath, Bikash; Lasheen, Deena S. ; Serya, Rabah A T; Abouzid, Khaled ; Neamati, Nouri |
| 1-Dec-2024 | Targeting apoptosis; design, synthesis and biological evaluation of new benzoxazole and thiazole based derivatives | Helmy, Sama W.; Shahin, Mai I. ; Samir, Nermin; Lasheen, Deena S. ; Ella, Dalal A.Abou El |
| Oct-2017 | Thiazolo[4,5-d]pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling study | Ewida, Menna A; Abou El Ella, Dalal ; Lasheen, Deena S. ; Ewida, Heba A; El-Gazzar, Yomna I; El-Subbagh, Hussein I |
| 15-Aug-2016 | Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivatives | Mowafy, Samar; Galanis, A; Doctor, Zainab M; Paranal, Raymond M; Lasheen, Deena S. ; Farag, Nahla A; Jänne, Pasi A; Abouzid, Khaled |
