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Bioorganic Chemistry

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Results 1-20 of 25 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
12025ADMET, docking, anticancer evaluations, design and synthesis of pyrazolo [1, 5-a] pyrimidines substituted with furan and phenyldiazene as dual EGFRT790M and VEGFR-2 inhibitorsAlsulaimany, Marwa; Abdulhaleem, M Felemban Athary; Alghamdi, Raed; Abd El-Sattar, Nour EA; Almadani, Sara A; Samman, Waad A; Alharbi, Hussam Y; Aljohani, Majed S; Tayeb, Saeed M; Nasr, Tamer; Kurls Ekram Anwer 
2Jun-2024Advances in the discovery of activin receptor-like kinase 5 (ALK5) inhibitorsMansour, Mai A; Hassan, Ghaneya S; Jaballah, Maiy Y; Abouzid, Khaled A M; Serya, Rabah 
32022Corrigendum to" Design and synthesis of novel isatin-based derivatives targeting cell cycle checkpoint pathways as potential anticancer agents"[Bioorg. Chem. 105 (2020) 104366].Yousef, Mohamed A; Ali, Ahmed M; Qayed, Wesam S; Farag, Hassan HA; Aboul-Fadl, Tarek; El-Sayed, Wael 
42026Corrigendum to" Nanogel delivered benzimidazole-triazole hybrids as potent multitarget inhibitors of topoisomerase and tubulin in triple-negative breast cancer"[Bioorg. Chem. 167 (2025) 109288]Almadani, Sara A; Soliman, Moataz A; Abdur-Rahman, Mariam; Bendif, Hamdi; Elfalleh, Walid; Samman, Waad A; Alghamdi, Raed; Aouad, Mohamed R; Zaki, Magdi EA; Ali, Mohamed 
51-Jul-2025Design and synthesis of novel Hydroxamate and non-Hydroxamate HDAC inhibitors based on Chromone and Quinazolone scaffoldsAshraf, Rosaline; Adel, Mai ; Ibrahim, Esraa; Haffez, Hesham; Soror, Sameh; Abouzid, Khaled A M; Serya, Rabah 
62020Design, molecular modeling and anticancer evaluation of thieno [2, 3-d] pyrimidine derivatives as inhibitors of topoisomerase IIEl-Metwally, Souad A; Khalil, A. K. ; El-Sayed, Wael 
7Dec-2014Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agentsAbdelazeem, Ahmed H; Gouda, Ahmed M; Omar, Hany A; Tolba, Mai 
8Oct-2025Design, synthesis and biological evaluation of triazolo[1,5-a]pyrimidine derivatives as new antiproliferative agents with multikinase inhibitory activityEldeeb, Assem H; Shahin, Mai I. ; Jaballah, Maiy Y; Elaraby, Ahmed R; Ibrahim, Tamer M; Elaasser, Mahmoud M; Abdel-Aziz, Hatem A; Lasheen, Deena S. ; Abou El Ella, Dalal A
92024Design, synthesis and cytotoxic evaluation of new thieno [2, 3-d] pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducersAboulMagd, Asmaa M; Nemr, Mohamed TM; Farag, Paula S; aya ibrahim hassaballah ; Hemdan, Magdy M; Abd El-Mawgoud, Heba K
102019Design, synthesis and molecular docking of novel pyrazolo[1,5-a][1,3,5]triazine derivatives as CDK2 inhibitorsOudah, Khulood H; Najm, Mazin A A; Samir, Nermin ; Serya, Rabah ; Khaled A M Abouzid 
11Mar-2019Design, synthesis and molecular modeling study of certain VEGFR-2 inhibitors based on thienopyrimidne scaffold as cancer targeting agentsGhith, Amna; Youssef, Khairia M; Ismail, Nasser S M; Abouzid, Khaled 
12Jan-2020Design, synthesis, biological evaluation and molecular modeling study of new thieno[2,3-d]pyrimidines with anti-proliferative activity on pancreatic cancer cell linesSalem, Mohamed S H; Abdel Aziz, Yasmine M; Elgawish, Mohamed S; Said, Mohamed M; Abouzid, Khaled 
13Aug-2020Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agentsMorcoss, Martha M; Abdelhafez, El Shimaa M N; Ibrahem, Reham A; Abdel-Rahman, Hamdy M; Abou El Ella, Dalal ; lhab Abdel Aziz Mohammed
142025Exploring the larvicidal and pupicidal activities of new functionalized pyridines against Culex pipiens L. referring to molecular docking and SAR studiesElewa, Safaa I; Tantawy, Ahmed H; Mohamed, Hany I; Lashin, Walaa H; Doaa Ramadan Abdel Haleem Ramadan 
1513-Aug-2022Facile synthesis, larvicidal activity, biological effects, and molecular docking of sulfonamide-incorporating quaternary ammonium iodides as acetylcholinesterase inhibitors against Culex pipiens LAhmed H. Tantawy a; Shaimaa M. Farag b; Hany I. Mohamed a; Doaa Ramadan Abdel Haleem Ramadan 
16Mar-2022Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessmentElgiushy, Hossam R; Mohamed, Sameh H; Sawaf, Hussein; Hassan, Zeinab; Abou-Taleb, Nageh A; El-Labbad, Eman M; Hassan, Ashraf S; Abouzid, Khaled A M; Abouzid, Khaled ; Ali Taha, Heba
171-May-2024Induction of breast cancer cell apoptosis by novel thiouracil-fused heterocyclic compounds through boosting of Bax/Bcl-2 ratio and DFT studyAbass, Eman ; Abd-Rabou, Ahmed A.; El-Atawy, Mohamed A.; Ahmed, Hoda A.; El-Farargy, Ahmed F.; Heba K. Abd El-Mawgoud 
182025Nanogel delivered benzimidazole-triazole hybrids as potent multitarget inhibitors of topoisomerase and tubulin in triple-negative breast cancerAlmadani, Sara A; Soliman, Moataz A; Abdur-Rahman, Mariam; Bendif, Hamdi; Elfalleh, Walid; Samman, Waad A; Alghamdi, Raed; Aouad, Mohamed R; Zaki, Magdi EA; Ali, Mohamed 
19Oct-2022New fluorinated diarylureas linked to pyrrolo[2,3-d]pyrimidine scaffold as VEGFR-2 inhibitors: Molecular docking and biological evaluationAdel, Mai ; Abouzid, Khaled 
20Apr-2023New trends in synthetic drugs and natural products targeting 20S proteasomes in cancersAtta, Hind; Alzahaby, Nouran ; Prof. Hamdy, Nadia M. ; Emam, Soha H; Sonousi, Amr; Ziko, Laila