Bioorganic & medicinal chemistry

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Bioorganic & medicinal chemistry

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Results 1-15 of 15 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
11-Aug-2011Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium spEbada, Sherif ; Schulz, Barbara; Wray, Victor; Totzke, Frank; Kubbutat, Michael H G; Müller, Werner E G; Hamacher, Alexandra; Kassack, Matthias U; Lin, Wenhan; Proksch, Peter
21-Aug-2015Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XIIIbrahim, Diaa A; Lasheen, Deena S. ; Zaky, Maysoun Y; Ibrahim, Amany W; Vullo, Daniela; Ceruso, Mariangela; Supuran, Claudiu T; Abou El Ella, Dalal 
315-Aug-2009Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitorsAbadi, Ashraf H; Ibrahim, Tamer M; Khaled A M Abouzid ; Lehmann, Jochen; Tinsley, Heather N; Gary, Bernard D; Piazza, Gary A
415-Aug-2008Design, synthesis and in vitro antitumor activity of 4-aminoquinoline and 4-aminoquinazoline derivatives targeting EGFR tyrosine kinaseAbouzid, Khaled ; Shouman, Samia
515-Feb-2022Discovery of a benzimidazole-based dual FLT3/TrKA inhibitor targeting acute myeloid leukemiaDokla, Eman ; Abdel-Aziz, Amal Kamal ; Milik, Sandra N.; McPhillie, Martin J.; Minucci, Saverio; Khaled A M Abouzid 
61-Apr-2012Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivativesIsmail, Mohamed A H; Abou El Ella, Dalal ; Khaled A M Abouzid ; Mahmoud, Amr H
71-Sep-2020An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic propertiesMohamed, Sameh H; Elgiushy, Hossam R; Hammad, Sherif F; Abou-Taleb, Nageh A; A M Abouzid, Khaled; Abouzid, Khaled ; Hassan, Zeinab; Ali Taha, Heba
815-Feb-2006Ligand design and synthesis of new imidazo[5,1-b]quinazoline derivatives as alpha1-adrenoceptor agonists and antagonistsIsmail, Mohamed A H; Aboul-Enein, Mohamed N Y; Abouzid, Khaled ; Serya, Rabah A T
9May-2026Ligand-Based Design of Novel Thiazole-Quinazolinone Hybrids with Dual Antimicrobial and Anti-Virulence Activity Targeting Staphylococcal Sortase AHammad, Shaymaa G; Aboul-Magd, Dina S; Ghorab, Mostafa M; Adel, Mai; Serya, Rabah ; El-Hossary, Ebaa M; El-Gazzar, Marwa G; Abouzid, Khaled A M
1015-May-2008Novel anti-inflammatory agents based on pyridazinone scaffold; design, synthesis and in vivo activityAbouzid, Khaled ; Bekhit, Salma A
111-Jan-2008Pyridazinone derivatives: design, synthesis, and in vitro vasorelaxant activityAbouzid, Khaled ; Abdel Hakeem, Maha; Khalil, Omnya; Maklad, Yosria
1215-Dec-2010Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligandsOsman, Noha A; Mahmoud, Amr H; Allarà, Marco; Niess, Raimund; Khaled A M Abouzid ; Di Marzo, Vincenzo; Abadi, Ashraf H
131-Dec-2025Tackling microbial resistance with 4H-chromen-4-one derivatives as a novel class of penicillin binding protein 2a inhibitorsShalaby, Menna-Allah W; Abutaleb, Nader S; Dokla, Eman M E; Elgammal, Yehia; Liang, Hsin-Wen; Abdallah, Inas A; Fishovitz, Jennifer; Seleem, Mohamed N; Abouzid, Khaled A M; Serya, Rabah 
141-Jul-2025Targeting DNA repair mechanisms: Spirobenzoxazinone and salicylamide derivatives as novel candidates for PARP-1 inhibition in cancer therapyKadry, Alaa Ahmed; Adel, Mai; Abubshait, Samar A; Yahya, Galal; Sharaky, Marwa; Abouzid, Khaled A M; Serya, Rabah 
1515-Aug-2016Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivativesMowafy, Samar; Galanis, A; Doctor, Zainab M; Paranal, Raymond M; Lasheen, Deena S. ; Farag, Nahla A; Jänne, Pasi A; Abouzid, Khaled