Department of Pharmaceutical Chemistry - Pharmacy

Cairo, Abbassia, EG

OrgUnit's Researchers publications
(Dept/Workgroup Publication)

Results 81-100 of 188 (Search time: 0.009 seconds).

Issue DateTitleAuthor(s)
611-Nov-2024Hibiscus schizopetalus boosts wound healing via restoring redox balance and hindering inflammatory responses in rats: Insights on metabolome profiling and molecular dockingGamal El-Din, Mariam I.; Mantawy, Eman M.; Said, Riham S.; Fahmy, Nouran M.; Fayez, Shaimaa; Shahin, Mai I. ; Nasr, Maha ; Elissawy, Ahmed M.
2215-Dec-2017How to train your inhibitor: Design strategies to overcome resistance to Epidermal Growth Factor Receptor inhibitorsMilik, Sandra N; Lasheen, Deena S; Serya, Rabah ; Abouzid, Khaled A M; Khaled A M Abouzid 
2313-Nov-2018Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axisGe, Xin; Pan, Min-Hong; Wang, Lin; Li, Wei; Jiang, Chengfei; He, Jun; Abouzid, Khaled ; Liu, Ling-Zhi; Shi, Zhumei; Jiang, Bing-Hua
24Mar-2022Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessmentElgiushy, Hossam R; Mohamed, Sameh H; Sawaf, Hussein; Hassan, Zeinab; Abou-Taleb, Nageh A; El-Labbad, Eman M; Hassan, Ashraf S; Abouzid, Khaled A M; Abouzid, Khaled ; Ali Taha, Heba
25Dec-2018Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modelingAdel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid 
268-Mar-2022Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluationMansour, Mai A; Oraby, Mamdouh A; Muhammad, Zeinab A; Lasheen, Deena ; Gaber, Hatem M; Khaled A M Abouzid 
2872019Identification of novel pyrazole and benzimidazole based derivatives as PBP2a inhibitors: Design, synthesis, and biological evaluationShalaby, Menna-Allah; Dokla, Eman ; Serya, Rabah ; Abouzid, Khaled 
2882018Imidazo[2',1':2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling studyEwida, Menna A; Abou El Ella, Dalal ; Lasheen, Deena S. ; Ewida, Heba A; El-Gazzar, Yomna I; El-Subbagh, Hussein I
289Jul-2013In silico design: extended molecular dynamic simulations of a new series of dually acting inhibitors against EGFR and HER2Ahmed, Marawan; Sadek, Maiada M; Abouzid, Khaled ; Wang, Feng
2904-May-2016Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivativesEldehna, Wagdy M; Abou-Seri, Sahar M; El Kerdawy, Ahmed M; Ayyad, Rezk R; Hamdy, Abdallah M; Ghabbour, Hazem A; Ali, Mamdouh M; Abou El Ella, Dalal 
2911-Dec-2021Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancerDokla, Eman ; Abdel-Aziz, Amal Kamal; Milik, Sandra N.; Mahmoud, Amr H.; Saadeldin, Mona Kamal; McPhillie, Martin J.; Minucci, Saverio; Khaled A M Abouzid 
29215-Jul-2015Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular dockingEldehna, Wagdy M; Fares, Mohamed; Ibrahim, Hany S; Aly, Mohamed H; Zada, Suher; Ali, Mamdouh M; Abou-Seri, Sahar M; Abdel-Aziz, Hatem A; Abou El Ella, Dalal 
2931-Jun-2022Induction of apoptosis using ATN as a novel Yes-associated protein inhibitor in human oral squamous cell carcinoma cellsChu, Po Chen; Dokla, Eman ; Hu, Jing Lan; Weng, Jing Ru
2942022Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: A case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitorsMilik, SN; Abdel-Aziz, AK; El-Hendawy, MM; El-Gogary, RI; Saadeldin, MK; Minucci, S; Klein, CD; Abouzid, Khaled 
2951-Apr-2012Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivativesIsmail, Mohamed A H; Abou El Ella, Dalal ; Khaled A M Abouzid ; Mahmoud, Amr H
2961-Jan-1984Investigations on the Stability of Famprofazon N‐OxideAbou El Ella, Dalal ; Neugebauer, Michael; Eid, Attiat; Ebied, Mohamed Y.; Rücker, Gerhard
2971-Sep-2020An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic propertiesMohamed, Sameh H; Elgiushy, Hossam R; Hammad, Sherif F; Abou-Taleb, Nageh A; A M Abouzid, Khaled; Abouzid, Khaled ; Hassan, Zeinab; Ali Taha, Heba
2981-Sep-2011Labeling and Biological Evaluation of 99mTc-Cefotaxime for infective Inflammation DiagnosisM. A. Motaleb; A. A. El Mohty; M. A. El Garhy; Mohamed abdel Hamid Ismail; Abouzid, Khaled ; Tamer M. Sakr
299Dec-2024Lead generation of Aurora-A kinase inhibitors: Using 3D-QSAR pharmacophore modeling, virtual screening, and molecular dockingSara A. Hesham; Shahin, Mai I. ; Samar Mowafy; Rabah A. T. Serya; Nahla A. Farag; Khaled A. M. Abouzid
30015-Feb-2006Ligand design and synthesis of new imidazo[5,1-b]quinazoline derivatives as alpha1-adrenoceptor agonists and antagonistsIsmail, Mohamed A H; Aboul-Enein, Mohamed N Y; Abouzid, Khaled ; Serya, Rabah A T