Abouzid, Khaled

khaled.abouzid@pharma.asu.edu.eg

Department of Pharmaceutical Chemistry - Pharmacy
Interests: Anticancer drug discovery, design and synthesis, Antimicrobial,
Internal ID: rp12178
  • 3,121 Scopus Citations
  • 592 PubMed Citations

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Full Name
Abouzid, Khaled
 
 
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Biography
Dr. Khaled Abouzid is a Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Prominent Scholar in Drug Discovery, Co-founding Director of Center of Drug Discovery and Development Research ASU He was nominated as the Acting Dean of the Faculty of Pharmacy, University of Sadat City from 8-2018 to 8-2022. He is currently a member of national pharmaceutical chemistry promotion committee
Dr. Abouzid’s research is directed towards drug discovery of bioactive small molecules with special emphasis on cannabinoids, targeted anticancer, anti-inflammatory, anti-viral anti-microbial agents and enzyme inhibitors. He has published over 150 research papers, two books and filed 14 patents in medicinal chemistry. He has Scopus H index of 28. He has supervised over 100 Master and PhD students in 7 universities. Dr Abouzid has research collaborations with German, British, Swedish, Canadian and US universities. He has also organized and presided over 34 international symposia and conferences.
Dr. Abouzid obtained his B.Sc. degree in Pharmaceutical Sciences from Cairo University in 1985, and his PhD. joint degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University and School of Pharmacy University of Connecticut, USA.
Dr. Abouzid started his career in 1995 as a lecturer of Organic Chemistry at Cairo University, Faculty of Pharmacy. In 2001, he moved to the Department of Pharmaceutical Chemistry, Ain Shams University, and was promoted to Associate Professor in 2003. He did postdoctoral work with Professor Jochen Lehman of the Friedrich-Schiller-Universität Jena, Germany.

Publications

Results 101-120 of 134 (Search time: 0.006 seconds).

Issue DateTitleAuthor(s)
1012020Synthesis, Biological Evaluation and In Silico Investigation of Novel Functionalized Imidazole-Based KDM6 InhibitorsSerya, Rabah ; El-Araby, Amr; Qassem, Omar; El-Sawy, Ezzat; El-Razaz, Eman; Abouzid, Khaled 
102Jan-2020Design, synthesis, biological evaluation and molecular modeling study of new thieno[2,3-d]pyrimidines with anti-proliferative activity on pancreatic cancer cell linesSalem, Mohamed S H; Abdel Aziz, Yasmine M; Elgawish, Mohamed S; Said, Mohamed M; Abouzid, Khaled 
103Jan-2020Synthesis and antimicrobial evaluation of new halogenated 1,3-Thiazolidin-4-onesHammad, Shaymaa G; El-Gazzar, Marwa G; Abutaleb, Nader S; Li, Daoyi; Ramming, Isabell; Shekhar, Aditya; Abdel-Halim, Mohammad; Elrazaz, Eman ; Seleem, Mohamed N; Bilitewski, Ursula; El-Hossary, Ebaa M; Khaled A M Abouzid 
10415-Jan-2020Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteriaAbutaleb, Nader S; Milik, Sandra N; Li, Daoyi; El-Baz, Karim; Shalaby, Menna-Allah W; Al-Karaki, Rawan; Nasr, Maha ; Klein, Christian D; Seleem, Mohamed N; Dokla, Eman ; Khaled A M Abouzid 
1059-Apr-2020Targeting YAP Degradation by a Novel 1,2,4-Oxadiazole Derivative via Restoration of the Function of the Hippo PathwayDokla, Eman ; Fang, Chun Sheng; Chu, Po Chen; Chang, Chih Shiang; Chen, Ching S.; Khaled A M Abouzid 
106Aug-2020Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitorsHadi, Soha R Abd El; Soliman, Dalia H; Elrazaz, Eman ; Khaled A M Abouzid ; Lasheen, Deena S. 
1071-Aug-2020Penicillin binding protein 2a: An overview and a medicinal chemistry perspectiveShalaby, Menna-Allah W; Dokla, Eman ; Serya, Rabah ; Khaled A M Abouzid 
10810-Aug-2020Design, synthesis and in silico studies of new quinazolinone derivatives as antitumor PARP-1 inhibitorsRamadan, Sayed ; Elrazaz, Eman ; Khaled A M Abouzid ; El- naggar, Abeer 
10918-Aug-2020Design, Synthesis, and Biological Evaluation of Novel 7H-[1,2,4]Triazolo[3,4-b][1,3,4]thiadiazine Inhibitors as Antitumor AgentsIsmail, Muhammad I; Mohamady, Samy; Samir, Nermin; Abouzid, Khaled 
11026-Aug-2020Elaborating piperazinyl-furopyrimidine based scaffolds as phosphoinositol-3-kinase enzyme alpha (PI3Kα) inhibitors to combat pancreatic cancerMansour, Mai A; Lasheen, Deena S. ; Gaber, Hatem M; Khaled A M Abouzid 
1111-Sep-2020An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic propertiesMohamed, Sameh H; Elgiushy, Hossam R; Hammad, Sherif F; Abou-Taleb, Nageh A; A M Abouzid, Khaled; Abouzid, Khaled ; Hassan, Zeinab; Ali Taha, Heba
112Dec-2020Design, synthesis and biological evaluation of a new thieno[2,3-d]pyrimidine-based urea derivative with potential antitumor activity against tamoxifen sensitive and resistant breast cancer cell linesSharaky, Marwa; Kamel, Marwa; Aziz, Marwa A; Omran, Mervat; Rageh, Monira M; Abouzid, Khaled ; Shouman, Samia A
1132021Medicinal Chemistry Strategies Towards SO2 Donors as Research Tools and Potential TherapeuticsEl-Labbad, Eman M; Ji, Xingyue; Abouzid, Khaled ; Wang, Binghe
1142021Lipid polymer hybrid nanocarriers as a combinatory platform for different anti-SARS-CoV-2 drugs supported by computational studiesAbdel-Bar, Hend Mohamed; Abdallah, Inas A.; Fayed, Marwa A. A.; Moatasim, Yassmin; Mostafa, Ahmed; El-Behairy, Mohammed Farrag; Elimam, Hanan; Elshaier, Yaseen A. M. M.; Abouzid, Khaled 
1152021Synthesis, In Silico and In Vitro Antimicrobial Evaluation of Cyanoketene S,N-Acetals and Their Pyrazoles Against Staphylococcus Aureus DNA Gyrase EnzymeAli, Shimaa; H.I. Faraag, Ahmed; Elgiushy, Hossam; Said, Taghred; askar, ahmed; Hassan, ashraf; Abouzid, Khaled ; Fouad, Sherif
116Apr-2021Structure- and Ligand-Based in silico Studies towards the Repurposing of Marine Bioactive Compounds to Target SARS-CoV-2Fayed, Marwa A A; El-Behairy, Mohammed Farrag; Abdallah, Inas A; Abdel-Bar, Hend Mohamed; Elimam, Hanan; Mostafa, Ahmed; Moatasim, Yassmin; Abouzid, Khaled ; Elshaier, Yaseen A M M
117Aug-2021Discovery of potent thieno[2,3-d]pyrimidine VEGFR-2 inhibitors: Design, synthesis and enzyme inhibitory evaluation supported by molecular dynamics simulationsElrazaz, Eman ; Serya, Rabah A T; Ismail, Nasser S M; Albohy, Amgad; Abou El Ella, Dalal ; Khaled A M Abouzid 
118Sep-2021Synthesis, in vitro biological investigation, and molecular dynamics simulations of thiazolopyrimidine based compounds as corticotrophin releasing factor receptor-1 antagonistsElgiushy, Hossam R; Abou-Taleb, Nageh A; Holz, George G; Chepurny, Oleg G; Pirmettis, Ioannis; Kakabakos, Sotirios; Karageorgos, Vlasios; Liapakis, George; Albohy, Amgad; Abouzid, Khaled ; Hammad, Sherif F
1191-Sep-2021Antimicrobial and Cytotoxicity Evaluation of New 3-Allyl-2-iminothiazolidin-4-onesHammad, Shaymaa G.; El-Gazzar, Marwa G.; Abdel-Halim, Mohammad; Elrazaz, Eman ; El-Hossary, Ebaa M.; Khaled A M Abouzid 
120Dec-2021Molecular design, synthesis and in vitro biological evaluation of thienopyrimidine-hydroxamic acids as chimeric kinase HDAC inhibitors: a challenging approach to combat cancerAbdel-Atty, Mona M; Farag, Nahla A; Serya, Rabah A T; Abouzid, Khaled ; Mowafy, Samar