Role of MRI diffusion tensor imaging in assessment of normal appearing white matter in cases of multiple sclerosis
Tarek Hamed Gomaa Hassan;
Abstract
Multiple sclerosis is a disabling neurological disorder that showed variable clinical presentations, variable disease courses and variable outcomes that prove crippling and even fatal at many cases.
The diagnosis of the disease is based on multiple clinical, laboratory and imaging tests among which MRI stands as the modality of choice between the imaging techniques.
Conventional MRI provides important morphologic regarding the brain and spinal cord involvement by demyelinating plaques and can assess important features like the brain atrophy, T2 burden of the disease, lesions’ enhancement and the presence of black holes. All are important for the diagnosis and follow up.
However the conventional MRI is of almost no value in assessing the normal appearing white matter which was proved by multiple pathologic studies to be directly and indirectly involved in the process of multiple sclerosis.
Diffusion tensor imaging is one of the new MR imaging techniques that can provide data beyond the level
152
The diagnosis of the disease is based on multiple clinical, laboratory and imaging tests among which MRI stands as the modality of choice between the imaging techniques.
Conventional MRI provides important morphologic regarding the brain and spinal cord involvement by demyelinating plaques and can assess important features like the brain atrophy, T2 burden of the disease, lesions’ enhancement and the presence of black holes. All are important for the diagnosis and follow up.
However the conventional MRI is of almost no value in assessing the normal appearing white matter which was proved by multiple pathologic studies to be directly and indirectly involved in the process of multiple sclerosis.
Diffusion tensor imaging is one of the new MR imaging techniques that can provide data beyond the level
152
Other data
| Title | Role of MRI diffusion tensor imaging in assessment of normal appearing white matter in cases of multiple sclerosis | Other Titles | دور الرنين الموتر الانتشارى فى تقييم مادة الدماغ البيضاء التي تبدو سليمة فى حالات التصلب المتناثر | Authors | Tarek Hamed Gomaa Hassan | Issue Date | 2017 |
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