Study of Neutrophil gelatinase-associated Lipocalin in septic patients with risk of Acute Kidney Injury in ICU.
ZoherAbd El- HadyFathey;
Abstract
Our study included 50 patients admitted togeneral ICUs of Nasser Institute Hospital.
Patient was followed for 1st 2 weeks of ICU admission and divided into 2 equal groups:
• Group A: 25 patients who developed AKI with estimation of serum NGAL twice:
Within 24 hour of admission.
At time of AKI development (stage 1) only.
• Group B: 25 patients who did not develop AKI.
Our study showed highly significance correlation between Serum NGAL as a marker of AKI at time of admission and after development of AKI.
The present study Showed that NGAL as highly predictor of AKI with highly specificityand sensitivity (80%).
The present studyShowed NGAL as a predictor of hemodialysis with specificity (55.6%) and sensitivity (75%).
The present studyShowed NGAL as a predictor of patient's outcome with specificity (47.4%) and sensitivity (50%).
The present study showed significant correlation between Serum NGAL as a marker of AKI and (AST, INR, K on admission and K at AKI) at time of AKI.
And no significance correlation between Serum NGAL as a marker of AKI and other laboratory data.
As conclusionswe support the use of NGAL as a biomarker for the prediction of AKI with highly specificity in septic patients in ICU.
Patient was followed for 1st 2 weeks of ICU admission and divided into 2 equal groups:
• Group A: 25 patients who developed AKI with estimation of serum NGAL twice:
Within 24 hour of admission.
At time of AKI development (stage 1) only.
• Group B: 25 patients who did not develop AKI.
Our study showed highly significance correlation between Serum NGAL as a marker of AKI at time of admission and after development of AKI.
The present study Showed that NGAL as highly predictor of AKI with highly specificityand sensitivity (80%).
The present studyShowed NGAL as a predictor of hemodialysis with specificity (55.6%) and sensitivity (75%).
The present studyShowed NGAL as a predictor of patient's outcome with specificity (47.4%) and sensitivity (50%).
The present study showed significant correlation between Serum NGAL as a marker of AKI and (AST, INR, K on admission and K at AKI) at time of AKI.
And no significance correlation between Serum NGAL as a marker of AKI and other laboratory data.
As conclusionswe support the use of NGAL as a biomarker for the prediction of AKI with highly specificity in septic patients in ICU.
Other data
| Title | Study of Neutrophil gelatinase-associated Lipocalin in septic patients with risk of Acute Kidney Injury in ICU. | Other Titles | دراسة الدلالة البيولوجية للكلى مادة الليبوكالين المصاحبة لانزيم الجيلاتينيز في مرضى وحدة الرعاية المركزة بتسمم بالدم مع خطورة حدوث فشل كلوي حاد | Authors | ZoherAbd El- HadyFathey | Issue Date | 2014 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.