EVALUATION OF CARDIOPULMONARY STATUS USING NONINVASIVE RESPIRATORY PROFILE MONITOR IN CHRONIC OBSTRUCTIVE LUNG DISEASE PATIENTS DURING LOW VENTILATION STRATEGY

Abstract

COPD is associated with an accelerated decline in lung function, as chronic inflammation causes changes and narrowing of the small airways. Destruction of the lung parenchyma, also by inflammatory processes, leads to the loss of alveolar attachments to the small airways and decreases lung elastic recoil; in turn, these changes diminish the ability of the airway to remain open during expiration (GOLD, 2011) Volumetric capnography is especially sensitive to disturbances affecting the efficiency of ventilation for gas exchange. Because lung homogeneity is a very fragile property, it is endangered in the majority of diseases that affect the airways, lung parenchyma, or alveolar microcirculation Capnography, has become an integral part of monitoring in intensive care unit and helps to prevent life threatening events, as it aids diagnosis and treatment (Romero et al, 2007) It is important for a physician to be familiar with the patho-physiology and respiratory mechanics in COPD and an understanding of expiratory airflow obstruction and dynamic hyperinflation helps in choosing the most appropriate ventilatory settings (Mckenzie et al, 2009). This study aimed to assess cardiac and pulmonary status of two COPD patients groups receiving mechanical ventilation with a low tidal volume strategy using non- invasive partial CO2 rebreathing monitor These patients consisting of two groups. Twenty COPD patients, their predominant pathology was chronic bronchitis and twenty patients their predominant pathology was emphysema disease. All patients will be subjected to full history taking, thorough clinical examination, chest x-ray, Electrocardiograph, arterial blood gases, complete blood picture, renal function, and follow up to (blood pressure, heart rate, central venous pressure and urine output).