STUDY ON THE EFFECTS OF TRANSCUTANEOUS ELECTRICAL MUSCLE STIMULATION ON EXPERIMENTAL FATTY LIVER Thesis

Abstract

Exercise is a major challenge for other organs, particularly for the liver due to its central role in maintenance of glucose and lipid homeostasis and its function as energy supplier for the working muscle (Wasserman and Cherrington , 1991). This model of exercise is suggested to induce physical response consistent with physical exercise where rhythmic TEMS – induced contraction was reported to cause increase in O2 demand , HR, minute ventilation compared to resting values in healthy adults ( Banerjee et al ., 2005) . In addition , fructose feeding for 3 weeks prior to electric muscle stimulation was mainly to establish fatty liver before TEMS , this was documented by the histological examination of the hepatic tissues of two to three rats at the end of this duration as well as the same findings in previous studies (Ackerman et al ., 2005 ; Chong Mary et al ., 2007 ; Rizkalla ,2010 ). Changes in body weight , BMI , abdominal and lower limb circumferences : - The significant reduction in the final body weight , BMI , abdominal and lower limb circumferences with fructose feeding could be attributed to fructose itself as it increases the ene