Role of Vitamin D in Chronic Rhinosinusitis

Abstract

Chronic rhinosinusitis (CRS) is defined as inflammation of the nose and paranasal sinuses for more than 12 weeks. Characterized by two or more symptoms. One of which should be nasal obstruction or nasal discharge. Confirmation of sinus-nasal mucosal inflammation via either endoscopic inspection or imaging is recommended to confirm the clinical diagnosis. The signs and symptoms of CRS include Nasal obstruction which is the most common symptom, facial pressure-congestion-fullness, nasal discharge and hyposmia. High fever is usually absent, but myalgias and fatigue are common. There is no one causative factor that accounts for CRS. There is evidence of numerous factors contributing to CRS as biofilms, osteitis, allergy, superantigens from Staphylococcus aureus, fungi, general host factors and infectious agent. Management of CRS usually medical includes antibiotics, a nasal steroid spray and nasal saline irrigation. Other drugs