Role of MRI in Postoperative Assessment and Detection of Recurrence in Cancer Rectum
Mohammed Adil Ali;
Abstract
Cancer rectum is one of the most common causes of cancer all over the world. It is considered the third most common cancer worldwide. Around 30-40% of colorectal cancers are located in the rectum.
Currently, surgical resection with stage appropriate neo-adjuvant combined modality therapy is the mainstay in the treatment of rectal cancer, the increasingly widespread adoption of total mesorectal excision (TME) has resulted in a dramatic decline in the prevalence of local recurrence from 38% to less than 10%. Tumor stage, depth of invasion, tumor involvement in CRM, the degree of vascular or perineural invasion, Stage of nodal involvement, presence or absence of distant metastasis all are predictors factors of tumor recurrence which in turns affecting survival rates.
Early detection of recurrent or metachronous disease will lead to effective treatment and a better survival rate. Imaging modalities for postoperative assessment and detection of recurrence include: Computed tomography (CT), magnetic resonance imaging (MRI) and fusion imaging (PET/CT).
Post-operative MRI and diffusion-weighted MRI (DW-MRI) has been reported high accuracy for the diagnosis of locally recurrent rectal cancer as DW-MRI clearly discriminates the abnormal signal intensity of tumor from surrounding organs such as the bowel or from fibrosis. It also proved to be valuable in the setting of associated sepsis or anastomotic leakage because it may differentiate between recurrence and inflammation on the basis of morphological features on T2 or enhanced T1-weighted MR images.
The purpose of this study is to assess the role of MRI in postoperative assessment and detection of recurrence in patient with surgically restrected cancer rectum. In this work 20 patients were subjected to assessment by MRI with pelvic phased array coil with no need to any preparations.
Rectal MR imaging with a phased-array surface coil yields high-spatial-resolution images, there by providing a full evaluation of the pelvic structures and high discrimination between normal and abnormal tissues, and has the additional advantage of a large field of view. Moreover, the use of a phased-array surface coil improves patient comfort and lacks the hazards of radiation as in CT and PET/CT.
T2-weighted MR imaging is the key sequence in the
Currently, surgical resection with stage appropriate neo-adjuvant combined modality therapy is the mainstay in the treatment of rectal cancer, the increasingly widespread adoption of total mesorectal excision (TME) has resulted in a dramatic decline in the prevalence of local recurrence from 38% to less than 10%. Tumor stage, depth of invasion, tumor involvement in CRM, the degree of vascular or perineural invasion, Stage of nodal involvement, presence or absence of distant metastasis all are predictors factors of tumor recurrence which in turns affecting survival rates.
Early detection of recurrent or metachronous disease will lead to effective treatment and a better survival rate. Imaging modalities for postoperative assessment and detection of recurrence include: Computed tomography (CT), magnetic resonance imaging (MRI) and fusion imaging (PET/CT).
Post-operative MRI and diffusion-weighted MRI (DW-MRI) has been reported high accuracy for the diagnosis of locally recurrent rectal cancer as DW-MRI clearly discriminates the abnormal signal intensity of tumor from surrounding organs such as the bowel or from fibrosis. It also proved to be valuable in the setting of associated sepsis or anastomotic leakage because it may differentiate between recurrence and inflammation on the basis of morphological features on T2 or enhanced T1-weighted MR images.
The purpose of this study is to assess the role of MRI in postoperative assessment and detection of recurrence in patient with surgically restrected cancer rectum. In this work 20 patients were subjected to assessment by MRI with pelvic phased array coil with no need to any preparations.
Rectal MR imaging with a phased-array surface coil yields high-spatial-resolution images, there by providing a full evaluation of the pelvic structures and high discrimination between normal and abnormal tissues, and has the additional advantage of a large field of view. Moreover, the use of a phased-array surface coil improves patient comfort and lacks the hazards of radiation as in CT and PET/CT.
T2-weighted MR imaging is the key sequence in the
Other data
| Title | Role of MRI in Postoperative Assessment and Detection of Recurrence in Cancer Rectum | Other Titles | دور التصوير بالرنين المغناطيسي في تقييم ما بعد الجراحة واكتشاف ارتجاع سرطان المستقيم | Authors | Mohammed Adil Ali | Issue Date | 2017 |
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