Single Dose Tamsulosin Versus Double Dose Tamsulosin in The Initial Management Of Patients Suffering from Acute Urinary Retention Due to Benign Prostatic Hyperplasia

Abstract

SUMMARY T his study was conducted upon 60 patients as a prospective randomized controlled trail comparing patients with AUR due to BPH by giving them medical treatment for one week in the form of single dose Tamsulosin and double dose Tamsulosin for the other group. Following the patients and complications of the catheter and drug side effects reported revealed that there is no significant statistical data of Tamsulosin in single or double dose groups. TWOC was performed for the patients after one week and the criteria of successful voiding include (flow rate of > 5 mL/s, a voided volume of > 100 mL and residual volume of 200 mL). In the absence of any internationally agreed outcome measures, investigators regarded a successful TWOC as effective bladder emptying. This study proved the superiority of the double dose Tamsulosin over the single dose Tamsulosin in a successful TWOC also improve the Qmax and post voiding residual urine. Also the IPSS improved with double dose more than with single dose group as reported by the patients. To summarize the study, it proved that it is better and more effective to use the double dose Tamsulosin as a medical treatment from the start for patients who had AUR caused by BPH without fearing the adverse effects of the drug. Also this study proved the importance of a TWOC after medical treatment for patients who had their first attack of AUR caused by BPH as the overall success rate was 63.3%. So we have to offer this chance for every patient in order to delay the need for any operations or to avoid it.