Hematological Disorders in Critically ill Patients

Mostafa Mahmoud Abdo Said;

Abstract


Hematologic disorders are frequently encountered in the intensive care unit, which include anemia, coagulation disorders, hematological malignancies and eosinophil disorders.

Anemia often develops early in the course of a critical illness. The causes of anemia in ICU include blood loss, blunted erythropoietin response, inflammation and increased RBCs destruction.

The established method for managing anaemia in the ICU is allogeneic red cell transfusion. The key question in deciding how to use red cell transfusion in the ICU is identifying the most appropriate transfusion trigger and the target haemoglobin range for each patient.

Recombinant human erythropoietin (rHuEPO) may represent a therapeutic option for the treatment of anemia of critical illness and an additional way to conserve RBCs in the ICU.

Coagulation disorders are commonly found in critically ill patients. They include bleeding disorders (hemorrhagic disorders) and clotting disorders (thrombotic disorders or hypercoagulable states).


Other data

Title Hematological Disorders in Critically ill Patients
Other Titles الإضطرابات الدمويه فى المرضى ذوى الحالات الحرجه
Authors Mostafa Mahmoud Abdo Said
Issue Date 2014

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