EXPERIMENTAL STUDIES ON THE EFFECT OF CADMIUM AS A POLLUTANT ON CERTAIN MAMMALIAN ORGANS
Hala Fahmy Abd-Ellah Sayed;
Abstract
he present investigation is performed to estimate the median lethal dose (LD5o) of cadmium chloride for male al-
bino rats Rattus norvegicus, weighing 100-110 g, and to study the harmful effects of three different concentrations (1/20
LD50• 1110 LD50 and 115 LD5o) of this metal on male rats from several points (mortality rate, morphology, hematology
as well as gross and histological features of the kidney and
testis).
The obtained results revealed that the subcutaneous
LD50 of cadmium chloride appeared to be 27.66 mg/kg body weight after 24 hours.
Rats treated with 1120 LD50 of cadmium chloride showed neither mortality nor severe symptoms, while they ex hibited retardation in growth throughout the whole experiment compared with the controls. in rats treated with 1/10 LD50
and 115 LD50 of cadmium chloride, mortality, behavioral al
terations and growth retardation-followed by a decrease in body weight-were recorded.
bino rats Rattus norvegicus, weighing 100-110 g, and to study the harmful effects of three different concentrations (1/20
LD50• 1110 LD50 and 115 LD5o) of this metal on male rats from several points (mortality rate, morphology, hematology
as well as gross and histological features of the kidney and
testis).
The obtained results revealed that the subcutaneous
LD50 of cadmium chloride appeared to be 27.66 mg/kg body weight after 24 hours.
Rats treated with 1120 LD50 of cadmium chloride showed neither mortality nor severe symptoms, while they ex hibited retardation in growth throughout the whole experiment compared with the controls. in rats treated with 1/10 LD50
and 115 LD50 of cadmium chloride, mortality, behavioral al
terations and growth retardation-followed by a decrease in body weight-were recorded.
Other data
| Title | EXPERIMENTAL STUDIES ON THE EFFECT OF CADMIUM AS A POLLUTANT ON CERTAIN MAMMALIAN ORGANS | Other Titles | دراسات تجريبية عن تأثير التلوث بالكادميوم على بعض الأعضاء فى حيوان ثديى | Authors | Hala Fahmy Abd-Ellah Sayed | Issue Date | 1996 |
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