Treatment of Bacterial Vaginosis by Oral Clindamycin as A Preventive Measure Of Preterm Labor

Abstract

It has become apparent from many studies that bacterial vaginosis approximately doubles the risk of spontaneous preterm delivery. But there is no statistical significant difference between Oral Clindamycin and placebo. So screening for bacterial vaginosis during the second trimester of pregnancy followed by administration in the positive cases has no significant in Oral Clindamycin prevention of preterm labour in pregnant women with a previous PTD. On the basis of this study it seems that Oral Clindamycin has no benefit in the prevention of preterm delivery in high risk women. We therefore do not recommend continued use of Oral Clindamycin in the clinical setting for the prevention of preterm delivery. Logistic regression analysis showed that bacterial vaginosis, consanguinity, previous abortion and history of repeated previous preterm labor could be considered as risk factors for subsequent preterm labor. Key words: Association Between Bacterial Vaginosis and Preterm Labor - Bacterial Vaginosis - The Vagina