MISOPROSTOL VERSUS METHYLERGOMETRIN IN PREVENTION OF POSTPARTUM HAEMORRHAGE AFTER CAESARIAN SECTION
Doha Abdel Aziz Mahdy;
Abstract
The aim of the present study is:
To compare the effectiveness of rectal Misoprostol (400ug) administered immediately preoperative with intramuscular Methylergometrine (0.2mg) in reducing blood loss during caesarean section and to compare the ability to maintain adequate uterine tone and to reduce the incidence and severity of postpartum haemorrhage
Study design:
Randomized controlled prospective study on 80 women were going to do Caesarean section 40 patients will receive immediately preoperative rectal Misoprostol (400ug) and 40 patients will receive after delivery of the foetus intramuscular Methylergometrine (0.2mg) .
The primary outcome:
The primary outcomes were to compare the occurrence of major obstetric haemorrhage and need for uterine massage and additional uterotonic agents. Secondary outcomes included estimated mean operative loss, objective changes in haemoglobin and haematocrite, preoperative and postoperative blood pressure and pulse, severe anaemia, need for blood transfusion, side effects and postnatal hospital stay.
Results:
Patients received misoprostol developed less postpartum haemorrhage, required less intervention with less mean operative blood loss.
Conclusion:
Misoprostol seems to be more effective in maintaining adequate uterine tone and preventing excessive blood loss in patients undergoing caesarean section.
To compare the effectiveness of rectal Misoprostol (400ug) administered immediately preoperative with intramuscular Methylergometrine (0.2mg) in reducing blood loss during caesarean section and to compare the ability to maintain adequate uterine tone and to reduce the incidence and severity of postpartum haemorrhage
Study design:
Randomized controlled prospective study on 80 women were going to do Caesarean section 40 patients will receive immediately preoperative rectal Misoprostol (400ug) and 40 patients will receive after delivery of the foetus intramuscular Methylergometrine (0.2mg) .
The primary outcome:
The primary outcomes were to compare the occurrence of major obstetric haemorrhage and need for uterine massage and additional uterotonic agents. Secondary outcomes included estimated mean operative loss, objective changes in haemoglobin and haematocrite, preoperative and postoperative blood pressure and pulse, severe anaemia, need for blood transfusion, side effects and postnatal hospital stay.
Results:
Patients received misoprostol developed less postpartum haemorrhage, required less intervention with less mean operative blood loss.
Conclusion:
Misoprostol seems to be more effective in maintaining adequate uterine tone and preventing excessive blood loss in patients undergoing caesarean section.
Other data
| Title | MISOPROSTOL VERSUS METHYLERGOMETRIN IN PREVENTION OF POSTPARTUM HAEMORRHAGE AFTER CAESARIAN SECTION | Authors | Doha Abdel Aziz Mahdy | Issue Date | 2016 |
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