Role of Infection in Acute Coronary Syndrome
Lamia Hamdy Ali;
Abstract
Introduction
INTRODUCTION & AIM OF THE 'VORK
Arteriosclerosis IS the main cause of coronary artery and cerebrovascular diseases which, in turn, are the most common causes of death in the industrialized world (Claudia, et al., 2002).
Progress has been made in the treatment of coronary artery disease (CAD) and •associated risk factors such as hypertension, diabetes, and dyslipidemia. Although the mortality rate due to coronary disease is declining, an estimated 50% of all cases are still not explainable on the basis of conventional risk factor(Etminan et al., 2004).
• As the common risk factors of atherosclerosis can explain only 50% of etiology of CAD, Therefore, looking for new risk factors of atherosclerosis is necessary (Pellicano etal., 2000).
Several infectious agents appear to increase the risk of CAD. The inflammatory infectious hypothesis of atherosclerosis has been reevaluated and increasing evidence suggests a linkage between infection and acute coronary syndrome (ACS). The discovery of heavy infectious load in the serum of patients with ACS might suggest a potential immunological mechanism (Di Tano et at., 2000).
INTRODUCTION & AIM OF THE 'VORK
Arteriosclerosis IS the main cause of coronary artery and cerebrovascular diseases which, in turn, are the most common causes of death in the industrialized world (Claudia, et al., 2002).
Progress has been made in the treatment of coronary artery disease (CAD) and •associated risk factors such as hypertension, diabetes, and dyslipidemia. Although the mortality rate due to coronary disease is declining, an estimated 50% of all cases are still not explainable on the basis of conventional risk factor(Etminan et al., 2004).
• As the common risk factors of atherosclerosis can explain only 50% of etiology of CAD, Therefore, looking for new risk factors of atherosclerosis is necessary (Pellicano etal., 2000).
Several infectious agents appear to increase the risk of CAD. The inflammatory infectious hypothesis of atherosclerosis has been reevaluated and increasing evidence suggests a linkage between infection and acute coronary syndrome (ACS). The discovery of heavy infectious load in the serum of patients with ACS might suggest a potential immunological mechanism (Di Tano et at., 2000).
Other data
| Title | Role of Infection in Acute Coronary Syndrome | Other Titles | دور العدوى فى متلازمة القصور الحاد للشرايين التاجيه | Authors | Lamia Hamdy Ali | Issue Date | 2005 |
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