STUDY ON THE INTERRELATIONSHIP BETWEEN GLUTATHIONE (GSH) AND THYROID HORMONES LEVELS IN LEUKAEMIAS, LYMPHOMAS AND SOME SOLID TUMORS

Abstract

In this study, Red cell GSH and serum thyroid hormones were estimated

m:

10 Acute lymphoblastic leukaemia patients (5 Patients before treatment and 5 patients after treatment). 10 Acute myeloid leukaemia patients (5 Patients before treatment and 5

patients after treatment).

10 Chronic lymphatic leukaemia patients (5 Patients before treatment and 5 patients after treatment). 10 Chronic myeloid leukaemia patients (5 Patients before treatment and

5 patients after treatment).

10 H.D patients (5 Patients before and 5 patients after treatment).

10 Nffi.., patients ( 5 Patients before and 5 patients after treatment ).

12 Breast cancer patients ( 6 Patients before and 6 patients after treatment). 8 Bladder cancer patients (4 patients before and 4 patients after

treatment ).

4 tissue biopsy ( 2 bladder cancer, 2 breast cancer and their adjacent normal tissues). The assays were also estimated in the sera and red cells of 10 ontrols .

I. Acute Leukaemia

A. GSH level

1. GSH level in All patients before treatment ( X 361.01 ± 140.83 ) was increased significantly as compared with controls (X 206.7 ± 19.22) and cases after treatment (X 164.36 ± 57.1).