Prevalence of glomerular diseases in Ain Shams University Hospitals

Abstract

GN is a major cause of morbidity and mortality from renal disease in many parts of the world, particularly in the tropical and sub¬tropical regions. According to several local registries and sporadic publications, it is responsible for about23.2 to 58.4% of patients on regular dialysis in the tropics, compared to contemporary areas of around 16-18% in the United States and 9-15% in Europe. It is responsible for 16.6%which has been reported in 1998 (Ibrahim et al., 2012). It varies in incidence among the different geographical areas due to socioeconomic conditions, ethnicity, genetic variability and environmental factors (Barsoum and Francis, 2000). Our study is cross sectional descriptive retrospective study was done in pathology center of Ain Shams University specialized hospital from 2011 to 2013. From all renal biopsy specimens, at least two cores of renal cortex were obtained and samples sent for light microscopy (LM) and immunofluorescence (IF) microscopy in all cases and for electron microscopy (EM) in select cases or where it could be afforded by the patient. Presence of at least one glomerulus is adequate for study under fluorescent microscope and electron microscope and presence of at least six glomeruli is adequate for light microscopic study.