Correlation Between Systemic And Portal Haemodynamic Changes And Serum Levels Of Nitric Oxide End Products In Cirrhotic Patients Before And After Endoscopic Variceal Obliteration By Ligation

Abstract

Bleeding from oesophageal varices is a major complication of portal hypertension and carries an extremely high mortality. The presence of different modalities for the management of oesophageal varices means that no one is fully accepted. Although endoscopic injection sclerotherapy (ETS) is currently tl1e most widely used treatment for the management of patients with oesophageal varices, it is associated with various local and systemic complications that may limit its effectiveness. o ln an attempt to reduce the incidence of these complicati9ns another endoscopic technique employing different principle has beeri explored. Based on the teclmique of band ligation of haemorrhoids, band ligation of oesophageal varices has been developed and adapted for use with the flexible endoscope. o The aim of the present work, is to study the changes in s'ystemic and portal haemodynamics and serum level of nitric oxide end products in cirrhotic patients and bleeding oesophagal varices before and after endoscopic variceal obliteration by ligation.