SOME IMMUNOLOGICAL ASPECTS IN CHILDREN UNDER G0lNG APPElNDICECTOMY

Abstract

Acute appendicitis is almost conunon during later childhood and early adult life. In developing countries, the incidence of appendicitis now appears to be increasing. Quick and accurate diagnosis of acute appendicitis is still a major problem, so every attempt should be made to increase diagnostic accuracy. The aim of this work is to evaluate some immunological aspects in

children suffering from appendicitis before and after appendicectomy, to correlate inununologic status with the degree of the disease and to evaluate the role of i1mnunological parameters in the diagnosis of appendicitis. One hundred patients of both sexes with age range of 7-15 years

were studied. All showed clinical manifestations of acute appendicitis and were going to be operated upon for appendicectomy. Twenty normal healthy voltmteer children, matching sex and age range, were studied as a control group. Tllis study was canied out at Zagazig University Hospital and

Zagazig general Hospital.

The patients, depending on histopathological examination of the excised appendices were classified into 3 groups; perforated appendicitis group, non-perforated appendicitis group and nonnal appendix group. All subjects were subjected to the following:

1) Detailed history taking with special attention to age, sex, abdominal pain, fever, anorexia, nausea and vomiting. 2) A thorough clinical examination with special attention to : temperature, pulse, abdominal tenderness and abdominal rigidity.