Clinical Profile And Histopathological Study Of Skin Tags In Egyptian Patients

Abstract

Skin tags is a common benign lesion composed of loose fibrous tissue and occurring mainly on the neck and major flexures as a small, soft, pedunculated protrusion, these lesions are very common, particularly in women at the menopause or later.

Skin tags are polypoid tumors with a flattened acanthotic and hyperpigmented epithelium, the dennis has loose connective tissue with dilated blood vessels, the protruding mass is connected to the skin by a narrow pedicle. The bulk of the lesion is loose, fibrous tissue, similar to that of the papillary dennis, the epidermis is thin, and the basal cell layer is flat and often hyperpigmented.

Skin tags had been described as a minor skin finding

111 diabetes mellitus. Through insulin resistance which is known with non-insulin dependent diabetes mellitus, insulin can activate the receptors specific to the mediators of growth hormone which are called insulin growth factors.