Role Of Radioiodine Ablation According To Risk Stratification In Well Differentiated Thyroid Carcinoma

Abstract

The aim of this study was to evaluate the role radioiodine ablation according to the risk stratification in well differentiated thyroid carcinoma. And evaluation of the role of 99mTc-SestaMIBI scan and serum Thyroglobulin in the follow up. • Our study was carried on 70 patients, 42 females and 28 males, their age ranged from 15-58 years, all of them were proved to have differentiated thyroid carcinoma 52 were papillary and 18 were follicular. Patients were classified according to the risk stratification into low risk group [ 30 patients ] and high risk group [40 patients ].All patients underwent whole body scanning using 131I and 99mTc-MIBI. Also, serum Tg was estimated during the follow up. Our results showed that Radioiodine-131 is the standard diagnostic method following surgery to evaluate extent of residual functioning thyroid tissue. Our finding suggests that 131I scintigraphy is a significantly more sensitive test than 99mTc-MIBI in detecting residual functioning thyroid tissue either in the pre. or

postab1ation group. The classification of patients according to their risk criteria is useful in planning the dose of 131I in ablation. Also, it is beneficial in certain age group [young age] and fertile age in adults. Repeated radioiodine ablative doses may be needed to reach complete ablation.