Central Venous Oxygen Saturation (ScvO2) as an Early Marker of Tissue Hypoxia and Early Predictor of Outcome after Pediatric Open Cardiac Surgery

Abstract

ow cardiac output & hypoxiais seen in up to 25% of patients after cardiopulmonary bypass.Low cardiac output syndrome is typically seen within 6-18 hours post-operatively, so it would be important to know that patients were followed for this amount of time, at a minimum. Cellular hypoxia and poor systemic perfusion may be present well before clinically apparent changes in cardiovascular responses are observed. Supplemental laboratory testing is essential for prompt recognition of LCOS and implementation of appropriate therapy.It is now generally accepted that a decreased central venous oxygen saturation (ScvO2) obtained from a central venous catheter, can reveal a mismatch between oxygen supply and oxygen demand, hence global tissue hypoxia. Lactate clearance is used diagnostically, therapeutically and prognostically. This prospective study aimed to assess the role o