EFFECTS OF INADVERTENT PERIOPERATIVE HYPOTHERMIA ON THE IMMUNE FUNCTIONS & OXYGEN CONSUMPTION
Ghada Mohamed Nabih Ahmed Bashandy;
Abstract
Inadvertent hypothermia is a frequent event during the perioperative period. While, decreases in body temperatures may exert organ protective effects under certain conditions, there is accumulating evidence that inadvertent perioperative hypothermia may also adversely affect organ function and outcome.
The aim of our current study was to find out the possible effects of mild inadvertent perioperative hypothermia on the immune system and total body 02 consumption, in comparison with intended normothermia in patients anesthetized with the two commonly used inhalational anesthetics, halothane and isoflurane.
It was found that inadvertent perioperative hypothermia adversely affects immune functions through suppression of IL-2 production postoperatively, and it causes a significant immediate postoperative increase in total body 02 consumption, an event that may especially
compromise patients with cardiopulmonary disease.
It was concluded that by preventing inadvertent perioperative hypothermia and maintaining normothermia we can prevent such
complications.
The aim of our current study was to find out the possible effects of mild inadvertent perioperative hypothermia on the immune system and total body 02 consumption, in comparison with intended normothermia in patients anesthetized with the two commonly used inhalational anesthetics, halothane and isoflurane.
It was found that inadvertent perioperative hypothermia adversely affects immune functions through suppression of IL-2 production postoperatively, and it causes a significant immediate postoperative increase in total body 02 consumption, an event that may especially
compromise patients with cardiopulmonary disease.
It was concluded that by preventing inadvertent perioperative hypothermia and maintaining normothermia we can prevent such
complications.
Other data
| Title | EFFECTS OF INADVERTENT PERIOPERATIVE HYPOTHERMIA ON THE IMMUNE FUNCTIONS & OXYGEN CONSUMPTION | Other Titles | تأثيرات الانخفاض الغير معتمد فى درجة حرارة الجسم عن المعدلات الطبيعية فى فترة ما حول العمليات الجراحية على الوظائف المناعية واستهلاك الاوكسجين بالجسم | Authors | Ghada Mohamed Nabih Ahmed Bashandy | Keywords | -Inadvertent- Perioperative-Hypothermia. Normothermia. -Immune functions - Cytokines - Interleukin-2 - lnterleukin-6- Tumor Necrosis Factor- a- Phagocytic activity. / -Total body 02 co!lsumption. | Issue Date | 2002 |
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