EXERCISE TOLERANCE IN TYPE 1 DIABETICS COMPARED WITH NORMAL YOUNG INDIVIDUALS
Yasser Bakr Mohamed;
Abstract
Background:
It is well known that insulin deficiency causes metabolic and hormonal impairments leading to abnormal substrate utilization during exercise. Objectives:
To study exercise tolerance in insulin dependant diabetics compared with
healthy individuals and hormone- substrate interplay during prolonged exercise to exhaustion
Methods:
Fifty-three patients and 15 healthy controls were subjected to exercise tolerance test after a 12-hour fasting period with estimation of blood glucose, serum lactate, and c-peptide before and after the exercise test. Results:
Duration of exercise to exhaustion was significantly lower in the diabetic group compared with the control group (66± 6.7 v 117 ± 9.4 minutes. P
<0.05). Glucose concentrations were significantly decreased at exhaustion in the diabetic group, Lactate concentrations were higher at exhaustion in the diabetic group, while c-peptide concentrations were maintained in the diabetic group and reduced in the control group.
Conclusion:
Diabetic subjects exercise tolerance is significantly lower compared with that of the control group when no insulin is administered for 12 hours. Prolonged exercise to exhaustion significantly reduces serum glucose concentration in diabetic patients.
It is well known that insulin deficiency causes metabolic and hormonal impairments leading to abnormal substrate utilization during exercise. Objectives:
To study exercise tolerance in insulin dependant diabetics compared with
healthy individuals and hormone- substrate interplay during prolonged exercise to exhaustion
Methods:
Fifty-three patients and 15 healthy controls were subjected to exercise tolerance test after a 12-hour fasting period with estimation of blood glucose, serum lactate, and c-peptide before and after the exercise test. Results:
Duration of exercise to exhaustion was significantly lower in the diabetic group compared with the control group (66± 6.7 v 117 ± 9.4 minutes. P
<0.05). Glucose concentrations were significantly decreased at exhaustion in the diabetic group, Lactate concentrations were higher at exhaustion in the diabetic group, while c-peptide concentrations were maintained in the diabetic group and reduced in the control group.
Conclusion:
Diabetic subjects exercise tolerance is significantly lower compared with that of the control group when no insulin is administered for 12 hours. Prolonged exercise to exhaustion significantly reduces serum glucose concentration in diabetic patients.
Other data
| Title | EXERCISE TOLERANCE IN TYPE 1 DIABETICS COMPARED WITH NORMAL YOUNG INDIVIDUALS | Other Titles | مقارنة مدى تحمل المجهود البدنى لمرضى السكر المعتمدين على الأنسولين ( النوع الأول ) والأشخاص الطبيعيين | Authors | Yasser Bakr Mohamed | Keywords | .Exercise, Diabetes, and Tolerance | Issue Date | 2000 |
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